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Postion:Product Catalog >API>Antibiotics>Other antibiotic Drugs>STAUROSPORINE
STAUROSPORINE
  • STAUROSPORINE
  • STAUROSPORINE
  • STAUROSPORINE
  • STAUROSPORINE
  • STAUROSPORINE

STAUROSPORINE NEW

Price Get Latest Price
Package 25KG
Min. Order: 1KG
Supply Ability: 50000KG/month
Update Time: 2023-08-01

Product Details

Product Name: STAUROSPORINE CAS No.: 62996-74-1
EC-No.: 613-127-7 Min. Order: 1KG
Purity: 99% Supply Ability: 50000KG/month
Release date: 2023/08/01

CAS:62996-74-1
MF:C28H26N4O3
MW:466.54
EINECS:613-127-7
Product Categories:Inhibitor;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Signalling;Protein Kinase Inhibitors and Activators;Protein Kinase;antibiotic;API
Mol File:62996-74-1.mol
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STAUROSPORINE Chemical Properties
Melting point 270°C
alpha D25 +35.0° (c = 1 in methanol); D22 +56.1° (c = 0.14 in methanol)
Boiling point 677.5±55.0 °C(Predicted)
density 1.56±0.1 g/cm3(Predicted)
RTECS KD5084000
storage temp. 2-8°C
solubility DMSO: soluble
form White to pale yellow solid
pka14.25±0.70(Predicted)
color Off white to pale yellow
Water Solubility Soluble in DMSO or ethanol.Soluble in dimethyl sulfoxide , dimethyl formamide, ethyl acetate, hot acetone and ethanol. Slightly soluble in chloroform and methanol. Insoluble in water.
BRN 1060573
Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 4 months.
InChIKeyHKSZLNNOFSGOKW-WIFUGMKFSA-N
CAS DataBase Reference62996-74-1

STAUROSPORINE Usage And Synthesis
DescriptionStaurosporine (Stsp) is potent inhibitor of protein kinase C (PKC) from rat brain, exhibiting an IC50 value of 2.7 nM. It inhibits rat recombinant PKC-α approximately 100- and 1,000-fold better than PKC-δ and PKC-ζ, respectively. However, Stsp is non-selective in that it also inhibits the activity of a variety of other protein kinases, not only PKC isoforms. The biological effects of Stsp include cytotoxicity, relaxation of smooth muscle, and regulation of eNOS gene expression.
Chemical PropertiesLight Yellow Solid
OccurrenceA complex alkaloid. staurosporine has been isolated from a strain of Streptomyces.
UsesStaurosporine is a protein Kinase C inhibitor that induces apoptosis in many cell types.
UsesStaurosporine is an unusual indolocarbazole alkaloid produced by a range of actinomycete species. It is a potent antitumour active, inducing apoptosis in a variety of cell lines. Staurosporine is a potent inhibitor of many kinases including protein kinase C, tyrosine kinase, CDK2/cyclin A and CDK4/cyclin D. At submicromolar concentrations, staurosporine inhibits both IKKalpha and IKKbeta.
DefinitionChEBI: Staurosporine is an indolocarbazole alkaloid and an organic heterooctacyclic compound. It has a role as an EC 2.7.11.13 (protein kinase C) inhibitor, a geroprotector, a bacterial metabolite and an apoptosis inducer. It is a conjugate base of a staurosporinium.

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Packing &shipping&Payment

Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
Quantity(Kilograms)1 - 10000>10000
Est. Time(days)5To be negotiated

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Article illustrationCompany information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.

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