SR59230A hydrochloride NEW
Price | $38 | $82 | $118 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-15 |
Product Details
Product Name: SR59230A hydrochloride | CAS No.: 1135278-41-9 |
Supply Ability: 10g | Release date: 2024/11/15 |
Product Introduction
Bioactivity
名稱 | SR59230A hydrochloride |
描述 | SR59230A hydrochloride (SR59230A HCl) is a blood-brain permeable, selective and highly potent β3-adrenergic receptor antagonist that inhibits ultradian brown adipose tissue thermogenesis and interrupts associated paroxysmal brain and body heating. |
體外活性 | SR59230A hydrochloride (100 nM-50 μM; 24 hours) can reduce cell viability in a dose-dependent manner in Neuro-2A, BE(2)C and SK-N-BE(2) NB cell lines. [1] |
體內(nèi)活性 | MDMA (20 mg/kg) caused a slow rise in body temperature, reaching a maximum temperature increase of 1.8°C at 130 min post-injection. SR59230A hydrochloride (0.5 mg/kg) was able to slightly but significantly alleviate the slow rise in body temperature induced by MDMA. SR59230A hydrochloride (5 mg/kg) exhibited a significant and pronounced early hypothermic response to MDMA. [2] |
存儲條件 | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 200 mg/mL(552.62 mM), Sonication is recommended. H2O : 1 mg/mL(2.76 mM), Sonication is recommended. |
關(guān)鍵字 | SR-59230A hydrochloride | SR59230A Hydrochloride |
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Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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