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Postion:Product Catalog >SR59230A hydrochloride
SR59230A hydrochloride
  • SR59230A hydrochloride

SR59230A hydrochloride NEW

Price $38 $82 $118
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-15

Product Details

Product Name: SR59230A hydrochloride CAS No.: 1135278-41-9
Supply Ability: 10g Release date: 2024/11/15

Product Introduction

Bioactivity

名稱SR59230A hydrochloride
描述SR59230A hydrochloride (SR59230A HCl) is a blood-brain permeable, selective and highly potent β3-adrenergic receptor antagonist that inhibits ultradian brown adipose tissue thermogenesis and interrupts associated paroxysmal brain and body heating.
體外活性SR59230A hydrochloride (100 nM-50 μM; 24 hours) can reduce cell viability in a dose-dependent manner in Neuro-2A, BE(2)C and SK-N-BE(2) NB cell lines. [1]
體內(nèi)活性MDMA (20 mg/kg) caused a slow rise in body temperature, reaching a maximum temperature increase of 1.8°C at 130 min post-injection. SR59230A hydrochloride (0.5 mg/kg) was able to slightly but significantly alleviate the slow rise in body temperature induced by MDMA. SR59230A hydrochloride (5 mg/kg) exhibited a significant and pronounced early hypothermic response to MDMA. [2]
存儲條件store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 200 mg/mL(552.62 mM), Sonication is recommended.
H2O : 1 mg/mL(2.76 mM), Sonication is recommended.
關(guān)鍵字SR-59230A hydrochloride | SR59230A Hydrochloride
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Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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