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Postion:Product Catalog >Natural Products>Flavonoids>Sophoraflavanone G
Sophoraflavanone G
  • Sophoraflavanone G

Sophoraflavanone G NEW

Price $41 $96 $165
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Sophoraflavanone G CAS No.: 97938-30-2
Purity: 99.88% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameSophoraflavanone G
DescriptionSophoraflavanone G (Kushenol F) (Kushenol F), isolated from Sophora flavescens, induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways.
In vitroSophoraflavanone G (0-100 μM; 24 hours) reduces HL-60 cell viability in a dose-dependent manner and induces apoptosis by activating caspase-3 and caspase-9, downregulating Bcl-2 and Bcl-xL, upregulating Bax, and releasing cytochrome c from mitochondria to cytoplasm, thus promoting apoptosis via the mitochondrially-mediated intrinsic pathway [1]. Additionally, Sophoraflavanone G (0-40 μM; 24 hours) inhibits MDA-MB-231 cell viability with an IC50 of 29.7 μM in a concentration-dependent manner [2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 25 mg/mL (58.89 mM)
KeywordsInhibitor | anti-infammatory | Sophoraflavanone G | HL60 | inhibit | Apoptosis
Inhibitors RelatedStavudine | 5-Fluorouracil | Myricetin | Meclizine dihydrochloride | Dextran sulfate sodium salt (MW 4500-5500) | Sodium 4-phenylbutyrate | L-Ascorbic acid | Metronidazole | Sorafenib | Tributyrin | Salicylic acid | Oleic acid
Related Compound LibrariesFlavonoid Natural Product Library | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Selected Plant-Sourced Compound Library | Natural Product Library | Natural Product Library for HTS | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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