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Postion:Product Catalog >Slingshot inhibitor D3
Slingshot inhibitor D3
  • Slingshot inhibitor D3

Slingshot inhibitor D3 NEW

Price $42 $98 $156
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-11

Product Details

Product Name: Slingshot inhibitor D3 CAS No.: 1715076-35-9
Purity: 99.53% Supply Ability: 10g
Release date: 2024/11/11

Product Introduction

Bioactivity

名稱Slingshot inhibitor D3
描述Slingshot inhibitor D3 (JHN76359) is a potent inhibitor of the Protein Phosphatase Slingshot.
體外活性Slingshot 1 had?IC50?value of 3 μM and Slingshot 2 had?Ki value of 3.9 μM.?Slingshot inhibitor D3 has similar inhibitory activitieswith Slingshot 1 and Slingshot 2.
體內(nèi)活性Slingshot inhibitor D3 (5 μM; 45 minutes; PC12 cells;) significantly blocks NGF-induced dephosphorylation of cofilin at 15 and 30 minutes. Slingshot inhibitor D3 (5 μM; 45 minutes; PC12 cells) significantly decreases the NGF-induced cell migration, consistent with its inhibitory role in cofilin dephosphorylation. Slingshot inhibitor D3 (HEK293 cells) specifically blocks angiotensin II-induced cofilin dephosphorylation. Slingshot inhibitor D3 prevents cofilin dephosphroylation through inhibition of Slingshot.
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 23.08 mg/mL (50 mM), Sonication and heating to 60℃ are recommended.
關(guān)鍵字Inhibitor | competitive | PC12 | reversible | selective | Slingshot inhibitor D-3 | HEK293 | Slingshot inhibitor D3 | JHN 76359 | Slingshot inhibitor D 3 | JHN-76359 | potent | inhibit
相關(guān)庫經(jīng)典已知活性庫 | 抑制劑庫 | 已知活性化合物庫 | 抗感染化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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