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Postion:Product Catalog >SLF1081851
SLF1081851
  • SLF1081851

SLF1081851 NEW

Price $51 $122 $197
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: SLF1081851 CAS No.: 2763730-97-6
Purity: 98.57% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameSLF1081851
DescriptionSLF1081851 is a Spns2 inhibitor. SLF1081851 inhibits S1P release with IC50 of 1.93 μM.
In vitroSLF1081851 (compound 16d) (0-5 μM; 18-20 h) inhibits S1P release with an IC50 value of 1.93 μM in Hela cells[1]. SLF1081851 (0-30 μM; 20 min) inhibits mSphK1 (recombinant mouse SphK) (10 μM) and mSphK2 (5 μM) in a dose-dependent manner and suggests at least 15-fold selectivity (SphK1 IC50≥30 μM; SphK2 IC50≈30 μM)[1].
In vivoSLF1081851 (20 mg/kg; i.p., 4 h postdose) significantly inhibits circulating lymphocytes and plasma S1P. SLF1081851 recapitulates the genetic phenotype of Spns2 null mice[1].
StorageShipping with blue ice.
Solubility InformationEthanol : 9.0 mg/mL (26.2 mM), Sonication is recommended.
Inhibitors RelatedFingolimod hydrochloride | SLP9101555 | Tyloxapol | ASP-4058 | Ki16198 | CYM50260 | Siponimod | Fingolimod | S1PR1 modulator 1 | Ozanimod | CYM50308 | Ki16425
Related Compound LibrariesBioactive Compound Library | Membrane Protein-targeted Compound Library | Inhibitor Library | Bioactive Compounds Library Max | GPCR Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Product name Price   Suppliers Update time
$2500.00/100mg
VIP1Y
TargetMol Chemicals Inc.
2024-11-19
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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