
Shield-1 NEW
Price | $163 | $372 | $592 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: Shield-1 | CAS No.: 914805-33-7 |
Purity: 99.22% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | Shield-1 |
Description | Shield-1 is a specific, high-affinity, and cell-permeable ligand for FK506-binding protein 12 (FKBP) and reverses instability by binding to mutant FKBP (mtFKBP), allowing conditional expression of mtFKBP fusion proteins. |
In vitro | METHODS: Transfected cells with mtFKBP-TRPV5 were treated with Shield-1 (1 μM, 24 hours), the ligand was washed out, and the mtFKBP-TRPV5 signal was subsequently measured at different time points. RESULTS mtFKBP-TRPV5 protein levels decreased rapidly with a half-life (t) of 2.53 ± 0.59 hours. [1] |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 250 mg/mL (333.82 mM) |
Keywords | FK506-binding protein | inhibit | Shield 1 | high-affinity ligand | destabilization domain | Inhibitor | Shield1 | Shld 1 | Shield-1 | Shld1 | HEK293 | FKBP | NIH3T3 | Shld-1 |
Related Compound Libraries | Bioactive Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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