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Postion:Product Catalog >SGC-AAK1-1
SGC-AAK1-1
  • SGC-AAK1-1

SGC-AAK1-1 NEW

Price $38 $73 $148
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: SGC-AAK1-1 CAS No.: 2247894-32-0
Purity: 99.65% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameSGC-AAK1-1
DescriptionSGC-AAK1-1, a potent and selective inhibitor of AAK1 (AP2-associated kinase 1), has an IC50 of 270 nM and a Ki of 9 nM, and serves as a chemical probe.
In vitrophosphorylation of AP2M1 (T156)significantly reduced by SGC-AAK1-1 (1.25 μM) and activates WNT-driven BAR activity compared in a dose-dependent manner in HT1080 cells. SGC-AAK1-1 blocks AAK1 kinase activity, resulting in increased β-catenin protein stability and β-catenin-dependent transcription.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 40 mg/mL (93.56 mM), Sonication and heating to 60℃ are recommended.
KeywordsAAK1 | BMP2K | pathway | kinase | Inhibitor | inhibit | associated | SGCAAK11 | Wnt | SGC-AAK-1-1 | AP2 | SGC AAK1 1 | SGC-AAK1-1
Inhibitors RelatedRSS0680 | LP-922761 | SM1-71 | (Iso)-BMT-124110 Formate | BMT-124110 | BMS-986176 | BMT-124110 Formate | LP-935509
Related Compound LibrariesAnti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Neuronal Signaling Compound Library | Kinase Inhibitor Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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