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Postion:Product Catalog >SD-1029
SD-1029
  • SD-1029

SD-1029 NEW

Price $85
Package 1mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-21

Product Details

Product Name: SD-1029 CAS No.: 118372-34-2
Supply Ability: 10g Release date: 2024/11/21

Product Introduction

Bioactivity

NameSD-1029
DescriptionSD-1029 is a?JAK2?inhibitor and a novel Stat3 activation inhibitor that inhibits Stat3 phosphorylation and JAK-STAT signaling.
In vitroSD-1029 inhibits EGFP-Stat3 nuclear translocation in BHK-21 and U-2OS cells and suppresses p-Stat3 levels in human breast and ovarian cancer cell lines including cell growth and induces apoptosis in OVCAR8TR ovarian cancer cells. [1] SD-1029 inhibits JAK2 phosphorylation and the phosphorylation of STAT1 and STAT3. SD-1029 strongly inhibits Tyk2 phosphorylation, implicating both JAK2 and Tyk2 as upstream requirements for IL-23-induced IL-23R expression. [2]
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
KeywordsSD-1029
Inhibitors RelatedDelgocitinib | Ruxolitinib | Nifuroxazide | Balsalazide sodium hydrate | Tofacitinib Citrate | Fludarabine | Niclosamide | Ruxolitinib phosphate | CASIN | Diosgenin | Niclosamide olamine | Artesunate

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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