SD-1029 NEW
Price | $85 |
Package | 1mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-21 |
Product Details
Product Name: SD-1029 | CAS No.: 118372-34-2 |
Supply Ability: 10g | Release date: 2024/11/21 |
Product Introduction
Bioactivity
Name | SD-1029 |
Description | SD-1029 is a?JAK2?inhibitor and a novel Stat3 activation inhibitor that inhibits Stat3 phosphorylation and JAK-STAT signaling. |
In vitro | SD-1029 inhibits EGFP-Stat3 nuclear translocation in BHK-21 and U-2OS cells and suppresses p-Stat3 levels in human breast and ovarian cancer cell lines including cell growth and induces apoptosis in OVCAR8TR ovarian cancer cells. [1] SD-1029 inhibits JAK2 phosphorylation and the phosphorylation of STAT1 and STAT3. SD-1029 strongly inhibits Tyk2 phosphorylation, implicating both JAK2 and Tyk2 as upstream requirements for IL-23-induced IL-23R expression. [2] |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Keywords | SD-1029 |
Inhibitors Related | Delgocitinib | Ruxolitinib | Nifuroxazide | Balsalazide sodium hydrate | Tofacitinib Citrate | Fludarabine | Niclosamide | Ruxolitinib phosphate | CASIN | Diosgenin | Niclosamide olamine | Artesunate |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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