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Postion:Product Catalog >S19-1035
S19-1035
  • S19-1035

S19-1035 NEW

Price $55 $84 $172
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: S19-1035 Purity: 100%
Supply Ability: 10g Release date: 2024/11/19

Product Introduction

Bioactivity

NameS19-1035
DescriptionS19-1035 is a potent and specific inhibitor of aldo-keto reductase 1C3 (AKR1C3), displaying an inhibitory concentration (IC50) of 3.04 nM. It is primarily utilized in tumor research.
In vitroS19-1035 demonstrates low cytotoxicity (0-100 μM ; 72 h or 96 h) and limited antitumor efficacy when used alone.[1] S19-1035 significantly reverses the resistance of doxorubicin-resistant breast cancer cell lines when administered at 10 μM for 8 days.[1]
In vivoSetrobuvir (200, 400, and 800 mg) BID were -2.1, -2.2, and -2.9 log10 IU/mL, respectively (vs ≤0.1 log10 IU/mL with placebo).[3]
StorageShipping with blue ice.
Solubility InformationDMSO : 112.5 mg/mL (315.3 mM), Sonication and heating to 60℃ are recommended.
Inhibitors RelatedCarvedilol phosphate hemihydrate | ASP-9521 | HTS07545 | Metronidazole | Resveratrol | Pasiniazid | Dicoumarol | NAD+ | Apocynin | Triclosan | AKR1C1-IN-1 | Setanaxib
Related Compound LibrariesBioactive Compound Library | Inhibitor Library | Mitochondria-Targeted Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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