(S)-3-Hydroxyphenylglycine NEW
| Price | $77 | $98 | $158 |
| Package | 1mg | 2mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: (S)-3-Hydroxyphenylglycine | CAS No.: 71301-82-1 |
| Purity: 99.18% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | (S)-3-Hydroxyphenylglycine |
| Description | (S)-3-Hydroxyphenylglycine is an agonist of group I metabotropic glutamate receptors (mGluRs). |
| In vitro | Hippocampal neurons in the slice preparation exhibit spontaneous synchronized bursting activity in the presence of picrotoxin, a γ-aminobutyric acid-A receptor antagonist. These synchronized bursts rarely exceed 500 ms in duration and thus resemble interictal discharges. Control shows one such synchronized burst, which typically consisted of an initial abrupt discharge 100–200 ms in duration (primary burst) followed by a series of briefer phasic discharges (secondary bursts). Addition of (S)-3-hydroxyphenylglycine (250–500 μM) significantly prolonged the synchronized burst duration, primarily via a marked increase in the number of secondary bursts. These prolonged discharges ranged from 1 to 7 s in duration (4,282 ± 1,060 ms, a 1,021?± 247% increase, n = 7), and the secondary bursts within each discharge gradually changed in amplitude and frequency[2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : < 1 mg/mL (insoluble） H2O : < 8.36 mg/mL |
| Keywords | (S) 3 Hydroxyphenylglycine | 3-Hydroxyphenylglycine | (S)3Hydroxyphenylglycine |
| Inhibitors Related | Evans blue | L-Glutamic acid monosodium salt | O-Phospho-L-serine |
| Related Compound Libraries | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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