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Postion:Product Catalog >Ruzasvir
Ruzasvir
  • Ruzasvir

Ruzasvir NEW

Price $191 $480 $687
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Ruzasvir CAS No.: 1613081-64-3
Purity: 97.01% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameRuzasvir
DescriptionRuzasvir (MK-8408) is a novel and potent pan-genotypic inhibitor of hepatitis C virus NS5A with antiviral activity.
In vitroRuzasvir (MK-8408) was developed as a novel NS5A inhibitor to improve upon the potency and barrier to resistance of early compounds. Ruzasvir inhibited HCV RNA replication with 50% effective concentrations (EC50s) of 1 to 4 pM in Huh7 or Huh7.5 cells bearing replicons for HCV genotype 1 (GT1) to GT7. The antiviral activity was modestly (10-fold) reduced in the presence of 40% normal human serum. The interaction of Ruzasvir with an NS3/4A protease inhibitor (grazoprevir) and an NS5B polymerase prodrug (uprifosbuvir) was additive to synergistic, with no evidence of antagonism or cytotoxicity.[1]
StorageShipping with blue ice.
Solubility InformationDMSO : 50 mg/mL (52.79 mM)
KeywordsRuzasvir
Inhibitors RelatedRibavirin | Artemisinin
Related Compound LibrariesBioactive Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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