Factory Provide High Quality API Ruxolitinib Powder CAS: 941678-49-5

Introduction

Product Name : Ruxolitinib

Othe name :(3R)-3-cyclopentyl-3-(4-{7H-pyrrolo[2,3-d]pyriMidin-4-yl}-1H-pyrazol-1-yl)propanenitrile

CAS No. 941678-49-5

EINECS No.1312995-182-4

Molecular Formula: C17H18N6

MW:306.37

Assay: 99%
Appearance: White powder
Melting Point :84-89°C (lit.)

Density :1.40 g/cm3(Predicted)

Storage :Keep in a cool, dry, dark location

Ruxolitinib is the first oral medication that used for the treatment of myelofibrosis. It is a small-molecule inhibitor of the tyrosine kinase (namely, JAK1 and JAK2) and is suitable for the treatment of intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia Vera myelofibrosis and post essential thrombocythemia myelofibrosis.

Function
1.It is used to treat myelofibrosis.
2.It is used to treat polycythemia vera.
Application
1.Myelofibrosis (a bone marrow disease) that is intermediate or high-risk.
2. Primary myelofibrosis.
3.Post-polycythemia vera myelofibrosis.
4.Post-essential thrombocythemia myelofibrosis.