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Postion:Product Catalog >RP 70676
RP 70676
  • RP 70676

RP 70676 NEW

Price $56 $137 $208
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: RP 70676 CAS No.: 136609-26-2
Purity: 98.89% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameRP 70676
DescriptionRP 70676 is a potent ACAT inhibitor(rat and rabbit ACAT with IC50 of 25 and 44 nM ).
In vitroRP 70676 is a potent rabbit arterial ACAT inhibitor with IC50 of 40 nM and has been shown to be an effective inhibitor of ACAT derived from a number of tissues and species including man. The IC50 values range from 21 nM for hamster liver ACAT to 108 nM for enzyme from the intestine of cholesterol fed rabbits; in human hepatic tissues(IC50 : 44 nM). Murine macrophages the compound has an IC50 of 540 nM in whole cell P388D.
In vivoIn NZW rabbits,RP 70676 (10 mg/kg, p.o.) is well absorbed with plasma levels.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 125 mg/mL (300.06 mM), Sonication is recommended.
KeywordsRP-70676 | RP70676 | RP 70676 | mono- acylglycerol acyltransferase | Inhibitor | inhibit | Diglyceride acyltransferase | Diacylglycerol acyltransferase | Acyltransferase | acyl-CoA:cholesterol acyltransferase
Inhibitors RelatedXanthohumol | Lecimibide | Cyclandelate | Eldacimibe | YM17E | 2-Furoic acid | Eflucimibe | Monatepil 2maleate | A 922500 | OSMI-1 | TMP-153 | PF-04620110
Related Compound LibrariesBioactive Compound Library | ReFRAME Related Library | Inhibitor Library | Lipid Metabolism Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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