RORγt Inverse agonist 6 NEW
Price | $94 | $238 | $353 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: RORγt Inverse agonist 6 | CAS No.: 1887161-80-9 |
Purity: 98.65% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | RORγt Inverse agonist 6 |
Description | RORγt Inverse agonist 6 is an agonist of RORγt inverse. RORγt Inverse agonist 6 can be used in research on Th17-driven autoimmune diseases. |
In vivo | RORγt Inverse agonist 6 (30 mg/kg; p.o.) inhibits the expression level of IL-17A by 59% compared to the vehicle after the oral administration at the tested dose. RORγt Inverse agonist 6 suppresses IL-17A gene expression by IL-23 stimulation in a mouse pharmacodynamics model. RORγt Inverse agonist 6 (1 mg/kg; p.o.) exhibits improved drug exposure with AUC of 1289 ng h/mL[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 45 mg/mL (79.64 mM), Sonication is recommended. |
Keywords | RORγt Inverse agonist-6 | RORγt Inverse agonist6 | RORγt Inverse agonist 6 | RORrt Inverse agonist 6 | RORgammat Inverse agonist 6 | ROR | RAR-related orphan receptor | Inhibitor | inhibit |
Inhibitors Related | S18-000003 | Cedirogant | T0901317 | GSK2981278 | Nobiletin | XY101 | Cholesterol | AZD-0284 | Melatonin | SR2211 | Cabozantinib hydrochloride | ML 209 |
Related Compound Libraries | Nuclear Receptor Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Metabolism Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library | Transcription Factor-Targeted Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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