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Postion:Product Catalog >API>Nervous system drugs>Antiparkinson Drugs>Ropinirole
Ropinirole
  • Ropinirole

Ropinirole NEW

Price $293 $722 $987
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-13

Product Details

Product Name: Ropinirole CAS No.: 91374-21-9
Supply Ability: 10g Release date: 2024/11/13

Product Introduction

Bioactivity

名稱Ropinirole
描述Ropinirole (SKF 101468) is a selective D2-like family receptor agonist whereas it has no affinity for the D1 receptors. It is an orally active, potent D3/D2 receptor agonist with a Ki of 29 nM for D2 receptor, which also has pEC50s of 7.4, 8.4 and 6.8 for hD2, hD3 and hD4 receptors, respectively. Ropinirole has the potential for the treatment of Parkinson's disease[1] [2].
體外活性Ropinirole has 10-20 times higher affinity for D 3 receptors than for D 2 and D 4 receptors. It is weakly active at α2-adrenoceptors and 5-HT2 receptors but inactive at 5-HT1, benzodiazepine and gamma-aminobu acid receptors or α1 and β-adrenoceptors [1] [2].
體內(nèi)活性Ropinirole, administered intraperitoneally at doses ranging from 0.1 to 10 mg/kg, effectively reduces intracranial self-stimulation thresholds and exhibits anxiolytic- and antidepressant-like properties, without impacting motor function or spatial memory [2].
存儲條件Shipping with blue ice.

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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