Ro 8-4304 NEW
| Price | $681 |
| Package | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-20 |
Product Details
| Product Name: Ro 8-4304 | CAS No.: 195988-65-9 |
| Supply Ability: 10g | Release date: 2024/11/20 |
Product Introduction
Bioactivity
| Name | Ro 8-4304 |
| Description | Ro 8-4304 Hydrochloride is an antagonist of NMDA receptor with IC50 of 0.4 μM |
| In vitro | Ro 8-4304 is a voltage-independent, non-competitive antagonist of NMDA receptors in rat cultured cortical neurones and exhibits a state-dependent mode of action similar to that described for ifenprodil.?The apparent affinity of Ro 8-4304 for the NMDA receptor increased in an NMDA concentration-dependent manner so that Ro 8-4304 inhibited 10 and 100 microM NMDA responses with IC50s of 2.3 and 0.36 microM, respectively.?Currents elicited by 1 microM NMDA were slightly potentiated in the presence of 10 microM Ro 8-4304, and Ro 8-4304 binding slowed the rate of glutamate dissociation from NMDA receptors |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Keywords | Ro 8-4304 | Ro 84304 | Ro 8 4304 |
| Inhibitors Related | (-)-Aspartic acid | Mephenesin | Quinolinic acid | Urethane | Halothane | Riluzole | Ifenprodil Tartrate | Bupivacaine hydrochloride monohydrate | O-Phospho-L-serine | Procaine hydrochloride | Memantine hydrochloride | UBP551 |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
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