RO-5963 NEW
Price | $106 | $346 | $499 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: RO-5963 | CAS No.: 1416663-77-8 |
Purity: 98% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | RO-5963 |
Description | RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively). |
In vitro | RO-5963 (10 μM, 24 hours) potently activates p53 and elevates p21 and MDM2 levels. RO-5963 (10-20 μM; 48 hours) displays much higher apoptotic activity than Nutlin in both MCF7 and ZR75-30 cell lines [1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 50 mg/mL (96.36 mM) |
Keywords | RO 5963 | RO5963 | RO-5963 |
Inhibitors Related | Milademetan | Alrizomadlin | Rotenone | XI-006 | RG7112 | DPBQ | BAY 1892005 | Indole-3-carbinol | Idasanutlin | Navtemadlin | RITA | P53R3 |
Related Compound Libraries | Bioactive Compound Library | Anti-Cancer Metabolism Compound Library | Inhibitor Library | PPI Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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