Ro 25-6981 NEW
| Price | $48 | $68 | $91 |
| Package | 1mg | 2mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-11 |
Product Details
| Product Name: Ro 25-6981 | CAS No.: 169274-78-6 |
| Purity: 99.44% | Supply Ability: 10g |
| Release date: 2024/11/11 |
Product Introduction
Bioactivity
| 名稱 | Ro 25-6981 |
| 描述 | Ro 25-6981 is a potent and selective activity-dependent NMDA receptors blocker containing the NR2B subunit with IC50s of 0.009 and 52 μM for cloned receptor subunit combinations NR1C/NR2B and NR1C/NR2A respectively. Ro 25-6981 can be used in studies about Parkinson's disease. |
| 體內(nèi)活性 | Ro 25-6981 (800 μg; intrathecally) shows significant analgesic effects on incision pain in rats and effectively attenuates postoperative hyperalgesia induced by remifentanil[3]. In 6-OHDA-lesioned rats, Ro 25-6981 (0.39-12.5 mg/kg; i.p.) dose-dependently induces contraversive rotations without stimulating locomotion in normal rats[4]. In male albino rats of Wistar strain, Ro 25-6981 (1 and 3 mg/kg; i.p.) exhibits activation- and age-dependent anticonvulsant action at early postnatal development and causes a significant decrease of N1–P2 amplitude at higher stimulation intensities at 3 mg/kg[5]. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 90 mg/mL (265.12 mM), Sonication is recommended. |
| 關(guān)鍵字 | Ro 25-6981 | Ro 256981 | Ro 25 6981 |
| 相關(guān)產(chǎn)品 | (-)-Aspartic acid | Mephenesin | Quinolinic acid | Urethane | Halothane | Riluzole | Ifenprodil Tartrate | Bupivacaine hydrochloride monohydrate | O-Phospho-L-serine | Procaine hydrochloride | Memantine hydrochloride | UBP551 |
| 相關(guān)庫 | 疼痛相關(guān)化合物庫 | 經(jīng)典已知活性庫 | 神經(jīng)退行性疾病化合物庫 | 抗抑郁癥化合物庫 | 神經(jīng)信號分子庫 | 神經(jīng)遞質(zhì)受體化合物庫 | 神經(jīng)保護(hù)化合物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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