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Postion:Product Catalog >RK-9123016
RK-9123016
  • RK-9123016

RK-9123016 NEW

Price $50 $75 $128
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: RK-9123016 CAS No.: 955900-27-3
Purity: 100% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameRK-9123016
DescriptionRK-9123016 is a SIRT2 inhibitor. RK-9123016 increases the acetylation level of eukaryotic translation initiation factor 5A (eIF5A), a physiological substrate of SIRT2, and reduces cell viability of human breast cancer cells accompanied with a decrease in c-Myc expression.
In vitroRK-9123016 inhibited the enzymatic activity of SIRT2 with an IC50 value of 0.18 μM but not other human sirtuin members including SIRT1 and SIRT3 at 100 μM in vitro electrophoretic mobility shift assay. RK-9123016 inhibited the SIRT2 activity in MCF-7 cells by concentration dependent manner (0-30 μM).
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 3.75 mg/mL (10 mM), Sonication is recommended.
KeywordsRK-9123016
Inhibitors RelatedJGB1741 | Sirtinol | Dihydrocoumarin | Resveratrol | SRT 2104 | Nicotinamide riboside | MC3482 | SIRT6-IN-5 | Salvianolic acid B | Fisetin | 3-TYP | Nicotinamide
Related Compound LibrariesDNA Damage & Repair Compound Library | Bioactive Compound Library | Epigenetics Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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