Product Details
| Product Name:
Ritanserin |
CAS No.:
87051-43-2 |
| Purity:
99.89% |
Supply Ability:
10g |
| Release date:
2024/11/19 |
Product Introduction
Bioactivity
| Name | Ritanserin |
| Description | Ritanserin (R 55667) is a long-acting, highly potent, relatively selective, orally bioavailable 5-HT2 receptor antagonist with an IC50 of 0.9 nM. |
| In vitro | METHODS: AML cell lines Kasumi-1 and KG-1α were treated with Ritanserin (R 55667) (10, 20, 30, 40, 50, 60 μM), and cytotoxicity was determined by CCK-8.
RESULTSRitanserin (R 55667) significantly reduced the proliferation activity of AML cells in a dose-dependent and time-dependent manner. [1]
Ritanserin (R 55667) has low activity against multiple receptors, including histamine-H1 (IC50, 35 nM), dopamine-D2 (IC50, 70 nM), adrenergic-α1 (IC50, 97 nM), and adrenergic-α2 receptors (IC50, 150 nM).[2] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 50 mg/mL (104.7 mM), Sonication is recommended.
|
| Keywords | Inhibitor | 5-hydroxytryptamine Receptor | inhibit | Serotonin Receptor | R-55667 | Ritanserin | 5-HT Receptor | Beta Receptor | Dopamine Receptor | Adrenergic Receptor | R55667 | Histamine Receptor |
| Inhibitors Related | Alverine citrate | Dapoxetine hydrochloride | Meclizine dihydrochloride | Lidocaine | Famotidine | Octopamine hydrochloride | Sodium butanoate | Oxolinic acid | Alginic acid |
| Related Compound Libraries | Pain-Related Compound Library | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Membrane Protein-targeted Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
-
CAS:773855-65-5
$575.00 / 1mg
-
CAS:34320-83-7
$46.00 / 5mg
-
CAS:42123-27-3
$129.00 / 1mg
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$1520.00/25mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2024-10-28 |
United States