Product Details
Product Name:
Rineterkib |
CAS No.:
1715025-32-3 |
Purity:
98.4% |
Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
Name | Rineterkib |
Description | Rineterkib (ERK-IN-1) is an inhibitor of RAF and ERK1/2 activating mutations in the MAPK pathway. |
In vivo | ERK-IN-1 (50, 75 mg/kg, p.o., qd/q2d, 27 days) treatment significantly reduces the tumor volume in the Calu-6 human NSCLC subcutaneous tumor xenograft model in mice. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 60 mg/ml (103.73 mM), Sonication is recommended.
|
Keywords | Raf | G12V | Extracellular signal regulated kinases | G12D | ERK | NSCLC | inhibit | G12C | MAPK | KRAS | Raf kinases | Inhibitor | Rineterkib |
Inhibitors Related | TBHQ | Notoginsenoside R1 | Regorafenib monohydrate | Lidocaine | Sorafenib | Astragaloside IV | Lidocaine hydrochloride | Regorafenib | Dabrafenib | Sorafenib tosylate | Honokiol | Tauroursodeoxycholate |
Related Compound Libraries | Bioactive Compound Library | Pain-Related Compound Library | Kinase Inhibitor Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$96.00/1mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-11-19 |