Rheb inhibitor NR1 NEW
Price | $84 | $198 | $328 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: Rheb inhibitor NR1 | CAS No.: 2216763-38-9 |
Purity: 99.72% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | Rheb inhibitor NR1 |
Description | Rheb inhibitor NR1 is a selective mTORC1 inhibitor that suppresses the phosphorylation of T389pS6K1 and enhances the phosphorylation of S473pAKT. |
In vivo | In male C57BL/6 mice aged 6-7 weeks (fasted for 16 hours), administration of the Rheb inhibitor NR1 (30 mg/kg; intraperitoneal injection; single dose) resulted in significantly reduced mTORC1 activity in both kidney and skeletal muscle. Additionally, a clear band shift for T37/464E-BP1 was observed in skeletal muscle[1]. |
Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 20 mg/mL (34.58 mM), Sonication is recommended. |
Keywords | Rheb inhibitor NR1 | Rheb inhibitor NR-1 |
Inhibitors Related | α-Hydroxyglutaric Acid Lithium | L-Leucine | Capivasertib | Sapanisertib | Everolimus | Bimiralisib | Tacrolimus | GDC0084 | Dihydromyricetin | Rapamycin |
Related Compound Libraries | Bioactive Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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