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Postion:Product Catalog >RG7834
RG7834
  • RG7834

RG7834 NEW

Price $31 $68
Package 1mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: RG7834 CAS No.: 2072057-17-9
Purity: 99.89% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameRG7834
DescriptionRG7834 (RO 7020322) is a highly selective and orally bioavailable inhibitor of HBV, targeting HBsAg, HBeAg, and HBV DNA with IC50s of 2.8 nM, 2.6 nM, and 3.2 nM, respectively, in dHepaRG Cells.
In vitroRG7834 ((S)-(+)-64) is a highly selective and orally bioavailable inhibitor of HBV, potently inhibiting HBV antigens (HBsAg and HBeAg) and HBV DNA with IC50s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG cells. RG7834 exhibits no activity against CYP3A4, CYP2D6, CYP2C9 (IC50s >50 μM) or the hERG channel.
In vivoIn HBV-infected human liver chimeric uPA-SCID mice,RG7834 shows anti-HBV efficacy. RG7834 (2, 14.5 mg/kg, p.o.) exhibits good oral bioavail ability, and with a half-life of 4.9 h in mice.
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 125 mg/mL (311.37 mM), Sonication is recommended.
KeywordsHepatitis B virus | RO7020322 | RG 7834 | inhibit | Inhibitor | RG-7834 | RG7834 | RO-7020322 | HBV
Inhibitors RelatedDoxorubicin hydrochloride | Osthole | RO8191 | Cetylpyridinium Chloride | Tenofovir Disoproxil Fumarate | Thiamine hydrochloride | 4,5-Dicaffeoylquinic acid | Vebicorvir | 4-Hydroxyacetophenone | Telbivudine | Tenofovir | Bifendate
Related Compound LibrariesBioactive Compound Library | ReFRAME Related Library | Anti-Viral Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Clinical Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Product name Price   Suppliers Update time
$31.00/1mg
VIP3Y
TargetMol Chemicals Inc.
2024-11-19
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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