Product Details
Product Name:
ReN-1869 |
CAS No.:
170149-99-2 |
Purity:
99.89% |
Supply Ability:
10g |
Release date:
2025/06/07 |
Product Introduction
Bioactivity
Name | ReN-1869 |
Description | ReN-1869 is a novel selective histamine H(1) receptor antagonist with anti-neurogenic pain and anti-inflammatory activity for the study of neurological diseases. |
In vivo | No adverse effects were observed in mice treated with ReN 1869 hydrochloride (300 mg/kg, oral); 0.01-10 mg/kg of ReN 1869 hydrochloride had antinociceptive effects in the rodent chemical nociception test, but not in the thermal test (hot plate and tail flick); ReN 1869 hydrochloride can amplify the analgesic effect of morphine, but does not show tolerance after long-term administration; ReN 1869 hydrochloride is effective against neurogenic inflammation (anterograde nerve stimulation, histamine-induced edema), but not against carrageenan-induced inflammation. [4] |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature. |
Keywords | ReN-1869 | NNC-051869 | NNC051869 | NNC 051869 | HistamineReceptor | Histamine Receptor | H1 receptor |
Inhibitors Related | Chlorphenesin | Histamine dihydrochloride | Meclizine dihydrochloride | Mirtazapine | Lidocaine | Famotidine | Mebhydrolin napadisylate | Sodium butanoate | Amitriptyline hydrochloride | Alginic acid | Trazodone hydrochloride | Mianserin hydrochloride |
Related Compound Libraries | Histamine & Melatonin Receptor-Targeted Compound Library | Bioactive Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Neurotransmitter Receptor Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$1520.00/25mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-10-28 |