天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Welcome to chemicalbook!
+1 (818) 612-2111
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >Biochemical Engineering>Inhibitors>Transmembrane Transporters>Calcium Channel Inhibitors>Ranolazine dihydrochloride
Ranolazine dihydrochloride
  • Ranolazine dihydrochloride

Ranolazine dihydrochloride NEW

Price $44 $62 $97
Package 50mg 100mg 200mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Ranolazine dihydrochloride CAS No.: 95635-56-6
Purity: 99.93% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameRanolazine dihydrochloride
DescriptionRanolazine dihydrochloride (Ranolazine 2HCl) , an antianginal agent, can treat arrhythmia via a novel mechanism of action (inhibition of the late phase of the inward sodium current), and do not affect blood pressure or heart rate.
In vitroRanolazine (5 mM and 10 mM) reversibly shortened the duration of twitch contractions and abolished postcontractions.Ranolazine bound more to sodium channels in the inactivated state. In cardiomyocytes, selective inhibition of late I (sodium) by Ranolazine reduced sodium-dependent calcium overload and attenuated ventricular repolarization and contraction, which correlated with abnormalities in heart failure and ischemia/reperfusion injury. In dog left ventricular myocytes, in a concentration-dependent manner Ranolazine was able to reversibly shorten myocyte action potential duration in response to 0.25/0.5 Hz stimulation.
In vivoRanolazine (5 mM and 10 mM) reversibly shortened the duration of twitch contractions and abolished postcontractions.Ranolazine bound more to sodium channels in the inactivated state. In cardiomyocytes, selective inhibition of late I (sodium) by Ranolazine reduced sodium-dependent calcium overload and attenuated ventricular repolarization and contraction, which correlated with abnormalities in heart failure and ischemia/reperfusion injury. In dog left ventricular myocytes, in a concentration-dependent manner Ranolazine was able to reversibly shorten myocyte action potential duration in response to 0.25/0.5 Hz stimulation.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 45 mg/mL (89.92 mM)
H2O : 50.1 mg/mL (100 mM)
KeywordsCalcium Channel | Ranolazine Dihydrochloride | RS43285 | Autophagy | RS-43285 | Sodium Channel | CVT-303 | Inhibitor | Ranolazine | Ranolazine dihydrochloride | inhibit | Ca2+ channels | CVT303 | Na+ channels | Ca channels | Na channels | CVT 303
Inhibitors RelatedStavudine | Phenytoin sodium | Sodium 4-phenylbutyrate | L-Ascorbic acid | Hydroxychloroquine | Guanidine hydrochloride | Taurine | Paeonol | Naringin | Gefitinib
Related Compound LibrariesBioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | EMA Approved Drug Library | Inhibitor Library | Neuroprotective Compound Library | FDA-Approved Drug Library | Anti-Cancer Approved Drug Library | Anti-Aging Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

You may like

Recommended supplier

Product name Price   Suppliers Update time
$44.00/50mg
VIP5Y
TargetMol Chemicals Inc.
2024-11-19
$10.00/1Kg/Bag
Hebei Zhanyao Biotechnology Co. Ltd
2021-11-19
$15.00/1KG
Zhuozhou Wenxi import and Export Co., Ltd
2021-06-26
$1.00/1kg
Hebei Jimi Trading Co., Ltd.
2019-04-10
$100.00/1KG
VIP7Y
Career Henan Chemical Co
2018-08-01
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
INQUIRY