(R)-(+)-Bay-K-8644 NEW
| Price | $52 | $123 |
| Package | 1mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: (R)-(+)-Bay-K-8644 | CAS No.: 98791-67-4 |
| Purity: 96.51% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | (R)-(+)-Bay-K-8644 |
| Description | (R)-(+)-Bay-K-8644 is a Ca2+ channel and dihydropyridine agonist that inhibits Ba2+ currents (IBa), induces central respiratory depression in cats, and inhibits platelet activation through competitive antagonism of thromboxane A2-prostaglandin H2 receptors. |
| In vitro | (R)-(+)-Bay-K-8644, a component of the racemic mixture Bay K 8644, is a well-known L-type Ca2+ channel agonist but functions as an inhibitor of Ba2+ currents (IBa) with an IC50 of 975 nM. At a concentration of 0.5 μM, it reduces IBa to 71±10% of the control level, demonstrating its efficacy in inhibiting Ba2+ currents. Notably, this compound acts as a calcium channel inhibitor, crucial for modulating calcium channel activity [2]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 100 mg/mL (280.66 mM) |
| Keywords | (R)(+)BayK8644 | (R) (+) Bay K 8644 | Bay K8644 | Bay-K 8644 | Bay K 8644 | Bay-K8644 | Bay-K-8644 | Bay K-8644 |
| Inhibitors Related | PHYTOL | Nisoldipine | L-Ascorbic acid | Lanthanum(III) chloride heptahydrate | Daidzein | Fenofibrate | Ethyl cinnamate | 5-Aminosalicylic Acid | Naringenin | 1-Octanol | 2,3-Butanediol | Icariin |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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