Quercetin NEW
| Price | $42 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-28 |
Product Details
| Product Name: Quercetin | CAS No.: 117-39-5 |
| Purity: 98.05% | Supply Ability: 10g |
| Release date: 2025/05/28 |
Product Introduction
Bioactivity
| Name | Quercetin |
| Description | Quercetin, a flavonoid natural product, is a SIRT1 activator. It is also a PI3K inhibitor, inhibiting PI3Kγ, PI3Kδ, and PI3Kβ with IC50 values of 2.4, 3.0, and 5.4 μM, respectively. Recognized as a heat shock protein inhibitor, Quercetin can significantly reduce exosome release in TII models by downregulating Hsp70 or Hsp90. |
| In vitro | In xenografts of human prostate cancer LNCaP and PC-3 cells, the combined administration of Quercetin (75 mg/kg) and 2-methoxyestradiol effectively inhibits tumor growth. |
| In vivo | Quercetin inhibits TNF-induced LDH release, reduces EC-dependent adhesion of neutrophils to bovine pulmonary artery endothelial cells (BPAEC), and also suppresses DNA synthesis and cell proliferation in these cells. As a PI3K inhibitor (IC50=2.4 - 5.4 μM), quercetin strongly inhibits PI3K and Src kinases, moderately inhibits Akt1/2, and has a slight effect on PKC, p38, and ERK1/2. |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 5.7 mg/mL (18.86 mM), Solution. H2O : < 1 mg/mL (insoluble or slightly soluble) Ethanol : 4 mg/mL (13.23 mM), Sonication is recommended. 10% DMSO + 50% peg 300 + 5% Tween +35% Saline : 10 mg/mL (33.09 mM), Solution. DMSO : 100 mg/mL (330.86 mM), Sonication is recommended. |
| Keywords | ReactiveOxygenSpecies | Reactive Oxygen Species | Quercetin | PI3Kδ | PI3Kγ | PI3K | Phosphoinositide 3-kinase | Mitophagy | Mitochondrial Autophagy | Inhibitor | inhibit | Autophagy | Apoptosis |
| Inhibitors Related | Stavudine | Cysteamine hydrochloride | Dextran sulfate sodium salt (MW 4500-5500) | Sodium 4-phenylbutyrate | Hydroxychloroquine | Guanidine hydrochloride | Tributyrin | Paeonol | Naringin | L-Ascorbic acid sodium salt | Alginic acid | Gefitinib |
| Related Compound Libraries | Marine Natural Product Library | Polyphenolic Natural Product Library | Flavonoid Natural Product Library | Selected Plant-Sourced Compound Library | Saccharide and Glycoside Natural Product Library | Natural Product Library | Antiparasitic Natural Product Library | Natural Product Library for HTS | Anti-Aging Compound Library | Bioactive Compounds Library Max | Ancient Chinese Classical Formulas Compound Library | Food as Medicine Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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