Product Details
| Product Name:
Prunetin |
CAS No.:
552-59-0 |
| Purity:
98% |
Supply Ability:
10g |
| Release date:
2025/06/17 |
Product Introduction
Bioactivity
| Name | Prunetin |
| Description | 1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesity-related transcription through a feedback mechanism that regulates the expression of adiponectin, adipoR1, adipoR2, and AMPK. 3. Prunetin and biochanin A are potent reducers of NF-κB and ERK activation, zonula occludens 1 tyrosine phosphorylation, and metalloproteinase-mediated shedding activity, which may account for the barrier-improving ability of these isoflavones. 4. Prunetin significantly suppresses ATP-induced mucin secretion from cultured RTSE cells; Prunetin inhibits the production of MUC5AC mucin protein induced by EGF or PMA from NCI-H292 cells; Prunetin also inhibits the expression of MUC5AC mucin gene induced by EGF or PMA from NCI-H292 cells. |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 50 mg/mL (175.9 mM), Sonication is recommended.
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc. : Soluble
|
| Keywords | rhinitis | Prunetin | NF-κB | NFκB | NF-kB | NFkB | nasal | liver | Inhibitor | inhibit | inflammatory | ERK | epithelial | cytokine | allosteric | allergic | ALDH | Aldehyde Dehydrogenase (ALDH) |
| Inhibitors Related | TBHQ | Rotenone | Mycophenolate Mofetil | Ribavirin | Methotrexate disodium | Diethylmaleate | Glucosamine | Lidocaine hydrochloride | Indole-3-carbinol | Diallyl disulfide | Isomalt | Nisin Z |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Flavonoid Natural Product Library | Pain-Related Compound Library | Bioactive Compound Library | Flavor Compound Library | Kinase Inhibitor Library | Natural Product Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Ancient Chinese Classical Formulas Compound Library | Food as Medicine Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
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Suppliers |
Update time |
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$0.00/1g |
VIP3Y
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Hangzhou ICH Biofarm Co., Ltd
|
2023-07-07 |
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$15.00/1KG |
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Zhuozhou Wenxi import and Export Co., Ltd
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2021-08-10 |
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$100.00/25KG |
VIP7Y
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Career Henan Chemical Co
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2018-07-26 |
United States