Protostemonine is an active alkaloid with anti-inflammatory activity, mainly isolated from Stemona sesslifolia root. Protostemonine has anti-inflammatory effects on asthma and acute lung injury caused by gram-negative bacteria.

Baibu is a commonly used effective Chinese medicine for the clinical treatment of cough, also known as "cough medicine", good at moistening the lungs to relieve cough, can be used to treat new cough, such as acute, chronic bronchitis, pertussis and tuberculosis and other diseases, the effect is exact. Chinese medicine Baifen has neither the addictive and respiratory depressant effects of morphine and codeine, nor the side effects of hallucination, delusion or other abnormal mental symptoms caused by dextromethorphan, so it has a broad development prospect. Hundred herbs are perennial herbs, originally published in the "Famous Doctor records", the herbs have been recorded in the past dynasties, the medicinal properties of sweet, bitter taste, return to the lung meridian, has the effect of moistening the lung and relieving cough. In the 2010 edition of Chinese Pharmacopoeia, the upright rhizome, the creeping rhizome and the dry root of the foliar rhizome were taken as the authentic rhizome. At present, the research on the activity of Baipu mainly focuses on its extracts, which are used in the treatment of respiratory diseases such as asthma, tuberculosis and whooping cough. Perinine is one of the main active components of perinine. According to its structure, perinine can be divided into stiniine type, primordial perinine type, perinine type, creeping perinine type and perinine type. Among them, protostemonine is the most widely distributed plant in Stemonaceae. At present, there are few reports on the activity of primordial alkaloid. Studies have shown that primordial line has a significant inhibitory effect on asthma, indicating that Primordial line has an important value in the treatment of clinical asthma, and provides a new direction for the search for anti-asthma drugs.