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Postion:Product Catalog >API>Antiparasitic drugs>Antimalarial drugs>Proguanil
Proguanil
  • Proguanil

Proguanil NEW

Price $35
Package 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-05-09

Product Details

Product Name: Proguanil CAS No.: 500-92-5
Purity: 99.6% Supply Ability: 10g
Release date: 2025/05/09

Product Introduction

Bioactivity

NameProguanil
DescriptionProguanil (Chloroguanide) is a prophylactic antimalarial drug that acts primarily through its active metabolite, Cycloguanil, which inhibits the dihydrofolate reductase (DHFR) enzyme of Plasmodium falciparum, preventing the synthesis of purines and pyrimidines and inhibiting the growth and reproduction of the parasite.
In vivoProguanil (2.9 mg/kg, orally, once daily) treatment of Wistar albino rats showed mild degenerative changes at day 5 and severe degenerative changes within 6 weeks, and resulted in a significant decrease in serum testosterone levels in the rats. [4]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationEthanol : 40 mg/mL (157.65 mM), Sonication is recommended.
DMSO : 120 mg/mL (472.94 mM), Sonication is recommended.
KeywordsProguanil
Inhibitors RelatedPemetrexed | 5-Fluorouracil | Rifaximin | Ribavirin | Guanidine hydrochloride | Methotrexate disodium | Trimethoprim | Cytarabine | Acyclovir | Thymidine | Temozolomide | Folic acid

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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