PROCYANIDIN C1 NEW
| Price | $72 | $322 | $537 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-16 |
Product Details
| Product Name: PROCYANIDIN C1 | CAS No.: 37064-30-5 |
| Purity: 98.87% | Supply Ability: 10g |
| Release date: 2025/05/16 |
Product Introduction
Bioactivity
| Name | PROCYANIDIN C1 |
| Description | Procyanidin C1 is a natural polyphenol that causes DNA damage, cell cycle arrest, and apoptosis induction. It reduces Bcl-2 protein levels and enhances the expression of BAX, caspase 3, and 9 in cancer cells. |
| In vitro | METHODS: PSC27 cells were treated with Procyanidin C1 (5, 10, 25, 50, 100, 400 μM) and senescent PSC27 cell survival was measured by SA-β-Gal staining. RESULTS Procyanidin C1 exerted an anti-senescent effect on senescent stromal cells starting at a concentration of 50 μM, at which concentration proliferating cells were largely unaffected. [1] METHODS: Procyanidin C1 (5 and 10 μM) was used in DLD1 and HCT116 cells, and the expression of has-miR-501-3p was detected. RESULTS Procyanidin C1 inhibited the expression of has-miR-501-3p in CRC cells with increasing concentrations. [4] |
| In vivo | METHODS: DLD1 and SW1463 cells were injected into the right axilla of BALB/c nude mice. The nude mice were treated with Procyanidin C1 (20 mg/kg and 40 mg/kg, intraperitoneal injection, once every three days), and the tumor volume and tumor weight were calculated. METHODS: Procyanidin C1 can inhibit tumor growth and metastasis in CRC, and the has-miR-501-3p/HIGD1A axis is involved in this process. [4] |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 30 mg/mL (34.61 mM), Sonication is recommended. |
| Keywords | PROCYANIDIN C-1 | PROCYANIDIN C1 | Procyanidin C 1 | PCC-1 | PCC1 | PCC 1 | Inhibitor | inhibit | Apoptosis protein | Apoptosis |
| Inhibitors Related | Stavudine | 5-Fluorouracil | Flubendazole | Cysteamine hydrochloride | Myricetin | Dextran sulfate sodium salt (MW 4500-5500) | Sodium 4-phenylbutyrate | L-Ascorbic acid | L-Glutamic acid | Tributyrin | L-Ascorbic acid sodium salt | Alginic acid |
| Related Compound Libraries | Polyphenolic Natural Product Library | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Selected Plant-Sourced Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library for HTS | Anti-Aging Compound Library | Bitter Compound library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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