Potassium 1H-indol-3-yl sulfate NEW
Price | $34 | $54 | $90 |
Package | 5mg | 10mg | 25mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-14 |
Product Details
Product Name: Potassium 1H-indol-3-yl sulfate | CAS No.: 2642-37-7 |
Purity: 99.71% | Supply Ability: 10g |
Release date: 2024/11/14 |
Product Introduction
Bioactivity
名稱 | Potassium 1H-indol-3-yl sulfate |
描述 | Potassium 1H-indol-3-yl sulfate (Potassium 3-indoxyl sulfate) is an agonist for the human Aryl Hydrocarbon Receptor (AhR), a key regulator of immune-inflammatory conditions. A metabolite of tryptophan derived from dietary protein, it is produced by intestinal bacteria and metabolized in the liver. In chronic kidney disease patients with impaired renal function, it accumulates in serum as a uremic toxin, inducing oxidative stress and accelerating disease progression. At 250 μM, it activates NF-Κb, promoting TGF-β1 and Smad3 expression in rat proximal tubular cells, which is associated with profibrotic activity. |
存儲條件 | store at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 3 months | Shipping with blue ice. |
溶解度 | DMSO : 100 mg/mL (397.93 mM), Sonication is recommended. H2O : 50 mg/mL (198.97 mM), Sonication is recommended. |
關(guān)鍵字 | Potassium 1H-indol-3-yl Sulfate | Potassium 1Hindol3yl sulfate | Inhibitor | Indoxyl sulfate potassium | Endogenous Metabolite | Potassium 3-indoxyl Sulfate | inhibit | Potassium 1H indol 3 yl sulfate |
相關(guān)產(chǎn)品 | Sucrose | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | Vanillin | Formamide | Glycerol | Thymidine | Naringin | 3-Indoleacetic acid | Oleic acid |
相關(guān)庫 | 表型篩選靶點鑒定庫 | 經(jīng)典已知活性庫 | 天然產(chǎn)物庫 | NO PAINS 化合物庫 | 高通量篩選天然產(chǎn)物庫 | 人內(nèi)源代謝化合物庫 | 人內(nèi)源代謝化合物庫 Plus | 已知活性化合物庫 | 腸道微生物代謝化合物庫 | 人代謝物化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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