Piperazine Erastin NEW
| Price | $88 | $177 | $297 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Piperazine Erastin | CAS No.: 1538593-71-3 |
| Purity: 97.74% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Piperazine Erastin |
| Description | Piperazine erastin, an analog of erastin, induces ferroptosis, an iron-dependent form of non-apoptotic cell death. |
| In vitro | Piperazine erastin is affected similarly by cell death modulators as erastin and displays a distinct pattern from other non-FIN lethal compounds. Piperazine erastin is a more effective analog of erastin which is more water-soluble (0.086 mM for erastin versus 1.4 mM for piperazine erastin) and more metabolically stable [1]. |
| In vivo | A significant delay in tumor growth is observed in the piperazine erastin-treated group compared to the vehicle-treated group, in the xenograft mouse model. Ptgs2 is upregulated in mouse liver with piperazine erastin (10 or 60 mg/kg) administration[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 65 mg/mL (100.75 mM), Sonication is recommended. |
| Keywords | Piperazine Erastin |
| Inhibitors Related | TBHQ | Acetylcysteine | α-Vitamin E | Sorafenib | L-Glutathione reduced | Curcumin | Artemisinin | L-Cystine | L-Glutamic acid monosodium salt | Coenzyme Q10 |
| Related Compound Libraries | Ferroptosis Compound Library | Apoptosis Compound Library | Bioactive Compound Library | Bioactive Compounds Library Max | Cell Cycle Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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