Pheniramine maleate NEW
Price | $38 | $50 | $93 |
Package | 50mg | 100mg | 500mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: Pheniramine maleate | CAS No.: 132-20-7 |
Purity: 99.79% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | Pheniramine maleate |
Description | Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived relaxing factor, nitric oxide. |
In vivo | Pheniramine maleate binds to histamine H1 receptors, which inhibits the production of phospholipase A2 and the endothelium-derived relaxing factor NO. This leads to a reduction in the activation of guanylate cyclase due to NO deficiency, resulting in decreased levels of cyclic GMP (cGMP). Consequently, this suppresses the contraction of smooth muscle tissues, reduces capillary permeability, and diminishes histamine-induced allergic responses. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | H2O : 65 mg/mL (182.4 mM) Ethanol : 66 mg/mL (185.2 mM) DMSO : 40 mg/mL (112.23 mM), Sonication is recommended. |
Keywords | Tripoton | spinal block | sedative | Prophenpyridamine | Pheniramine Maleate | Pheniramine maleate | Pheniramine | lumbar puncture | Jurkat ALL | Inhibitor | inhibit | hypnotic | human T-cell acute lymphoblastic leukemia | Histamine Receptor | first-generation | CNS | central nervous system | CCRF-CEM | Ca2+ influx | BC3H-1 | Apoptosis | antipruritic | antiemetic |
Inhibitors Related | Alverine citrate | Meclizine dihydrochloride | Dapoxetine hydrochloride | CLOZAPINE N-OXIDE | Lidocaine | Famotidine | Amitriptyline hydrochloride | Alginic acid | Trazodone hydrochloride | Mianserin hydrochloride | Fluoxetine hydrochloride | Cinchonidine |
Related Compound Libraries | Anti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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