PF-04979064 NEW
Price | $31 | $53 | $107 |
Package | 5mg | 10mg | 25mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: PF-04979064 | CAS No.: 1220699-06-8 |
Purity: ≥98% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | PF-04979064 |
Description | PF-04979064 is a potent and selective PI3K and mTOR dual kinase inhibitor, with Ki values of 0.13 nM and 1.42 nM, respectively. |
In vivo | PF-04979064 was tested against human class I PI3K isoforms α, γ, and δ, with PI3Kα Ki of 0.130 nM, PI3Kγ Ki of 0.111 nM, and PI3Kδ Ki of 0.122 nM.PF-04979064 was progressed to rat in vivo PK studies and exhibited robust PK profile: Vdss = 5.23 L/kg, Cl = 19.3 mL/min/kg, T1/2 = 1.85 h, and F % = 61%. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 4.46 mg/mL (10 mM), Sonication is recommended. |
Keywords | Inhibitor | PF-04979064 | Phosphoinositide 3-kinase | Mammalian target of Rapamycin | PF 04979064 | mTOR | PI3K | PF04979064 | inhibit |
Inhibitors Related | L-Leucine | Capivasertib | Myricetin | Erucic acid | Sapanisertib | (2S,3R,4S)-4-Hydroxyisoleucine | Duvelisib (R enantiomer) hydrochloride | Isoprenaline hydrochloride | Quercetin | Quercetin Dihydrate | Rapamycin | Apilimod |
Related Compound Libraries | Reprogramming Compound Library | Anti-Pancreatic Cancer Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Anti-Breast Cancer Compound Library | Inhibitor Library | Metabolism Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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