Product Details
| Product Name:
Peimisine |
CAS No.:
19773-24-1 |
| Purity:
99.26% |
Supply Ability:
10g |
| Release date:
2024/11/19 |
Product Introduction
Bioactivity
| Name | Peimisine |
| Description | 1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Peimisine can attenuate lung tissue injury( ALI), LDH and MDA amount in ALI mice in a dose dependent manner, it also lower the total protein, total white blood cells, lymphocyte and neutrophilic leukocyte in bronchoalveolar lavage fluid( BALF); suggests that peimisine can play a protective role against LPS-induced acute lung injury. 3. Peimisine has the protective effect on the experimental hepatic fibrosis formation, the possible mechanisms are associated with inhibiting fibrogenesis and fibrosis accumulation, and decreasing lipid peroxidation. 4. Peimisine can inhibit angiotensin I converting enzyme activity in a dose-dependent manner, displaying 5 % inhibitory concentration values of 526.5 microM, thus, it may have antihypertensive action. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 9 mg/mL (21.05 mM), Sonication is recommended.
|
| Keywords | muscarinic M receptor | antihypertensive activity | A549 | asthma | cough | anti-tumor activity | angiotensin converting enzyme | anti-inflammatory activity | HepG2 | Inhibitor | induce apoptosis | Angiotensin-converting Enzyme (ACE) | Muscarinic acetylcholine receptor | A2780 | inhibit | LLC | ACE | mAChR | Peimisine |
| Inhibitors Related | Adiphenine hydrochloride | Nanofin | Tranilast | CLOZAPINE N-OXIDE | Pilocarpine nitrate | Ribavirin | Sacubitril/Valsartan | Choline chloride | Propoxur | Irbesartan | Losartan | Captopril |
| Related Compound Libraries | Anti-Neurodegenerative Disease Compound Library | Traditional Chinese Medicine Monomer Library | Alkaloid Natural Product Library | Membrane Protein-targeted Compound Library | Selected Plant-Sourced Compound Library | Natural Product Library | Inhibitor Library | Natural Product Library for HTS | Bioactive Compounds Library Max | Ancient Chinese Classical Formulas Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
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Suppliers |
Update time |
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$0.00/25kg |
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Shaanxi Haibo Biotechnology Co., Ltd
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2023-08-24 |
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$8.00/1KG |
VIP6Y
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Career Henan Chemical Co
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2020-02-20 |
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$0.00/20mg |
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Shanghai Standard Technology Co., Ltd.
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2019-12-12 |
United States