
PDE4-IN-10 NEW
Price | $2140 | $2785 | $3520 |
Package | 25mg | 50mg | 100mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-05-02 |
Product Details
Product Name: PDE4-IN-10 | CAS No.: 2413564-66-4 |
Supply Ability: 10g | Release date: 2025/05/02 |
Product Introduction
Bioactivity
Name | PDE4-IN-10 |
Description | PDE4-IN-10 (compound 7a) is a potent PDE4 inhibitor with an IC50 of 7.01 μM for PDE4B, demonstrating selectivity, microsomal stability, TNF-α inhibition, and no major toxicities in vitro [1]. |
In vitro | PDE4-IN-10 (compound 7a) demonstrates selective inhibition of PDE4B, with 64.56% inhibition at 10 μM and 54% at 30 μM, compared to 17% inhibition of PDE4D at 10 μM, indicating a ~3.8-fold selectivity for PDE4B over PDE4D [1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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