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Postion:Product Catalog >PD 198306
PD 198306
  • PD 198306

PD 198306 NEW

Price $58 $141 $198
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: PD 198306 CAS No.: 212631-61-3
Purity: 99.75% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NamePD 198306
DescriptionPD 198306 is a selective inhibitor of MAPK/ERK-kinase (MEK) with antihyperalgesic effects. PD 198306 reduces the Streptozocin-induced increase in the level of active ERK1.
In vitroPD 198306 (10?μM) reduces Tha-Crimson replication by 30% at 18?h and 50% at 36?h. PD 198306 (10? μM) significantly inhibits Tha-GFP replication by 25%[1].
In vivoIn male Sprague Dawley rats bearing neuropathic pain, PD 198306 (1-30 μg/10 μL; i.t.) dose-dependently blocks static allodynia in both the chronic constriction injury and the streptozocin models[2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 45 mg/mL (94.49 mM)
KeywordsMAPK | inhibit | neuropathic | Inhibitor | MAP2K | rabies | mitogen-activated protein | drug | MAPKK | phosphatases | inositol | RNA | pain | PD198306 | interference | MEK | ERK | PD 198306 | antihyperalgesic | screening | Mitogen-activated protein kinase kinase | phosphate | kinases | PD-198306
Inhibitors RelatedLidocaine | Refametinib R enantiomer | Binimetinib | Lidocaine hydrochloride | Selumetinib | U0126-EtOH | Refametinib | Honokiol | Pelitinib | Trametinib | PD184161 | PD98059
Related Compound LibrariesAnti-Colorectal Cancer Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Kinase Inhibitor Library | Anti-Obesity Compound Library | Inhibitor Library | Anti-Prostate Cancer Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Liver Cancer Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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