Product Details
Product Name:
OXFBD04 |
CAS No.:
2231747-03-6 |
Purity:
98.84% |
Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
Name | OXFBD04 |
Description | OXFBD04 is a potent and selective BRD4 inhibitor (IC50= 166 nM), a BET bromodomain ligand with modest affinity for the CREBBP bromodomain, and exhibits anti-cancer activity. |
In vitro | OXFBD04 (0.01-100 μM) inhibits the cell growth of cancer cell lines. In MCF7 breast cancer cells, OXFBD04 (10?μM) induces MYC suppression[1]. |
In vivo | OXFBD04 has optimized physicochemical properties (LE = 0.43; LLE = 5.74; SFI = 5.96), and greater metabolic stability (t1/2 = 388?min, CLint = 3.57 μL/min/mg)[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 225 mg/mL (759.3 mM)
|
Keywords | OXFBD 04 | OXFBD04 | OXFBD-04 |
Inhibitors Related | ABBV-744 | CeMMEC1 | 3-methyl-1,2,3,4-tetrahydroquinazolin-2-one | (+)-JQ-1 | J-147 | Anacardic Acid | Curcumin | dBET6 | Piflufolastat | Naphthol AS-E | Bisdemethoxycurcumin | GSK1379725A |
Related Compound Libraries | Bioactive Compound Library | Epigenetics Compound Library | Kinase Inhibitor Library | Inhibitor Library | PPI Inhibitor Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
-
CAS:1599440-33-1
$39.00 / 1mg
-
CAS:57248-88-1
$38.00 / 5mg
-
CAS:284461-73-0
$34.00 / 50mg
Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$58.00/1mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-11-19 |