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Postion:Product Catalog >Organic Chemistry>Organometalate>Osimertinib mesylate
Osimertinib mesylate
  • Osimertinib mesylate
  • Osimertinib mesylate
  • Osimertinib mesylate
  • Osimertinib mesylate
  • Osimertinib mesylate

Osimertinib mesylate NEW

Price Get Latest Price
Package 25kg
Min. Order: 1kg
Supply Ability: 2000ton
Update Time: 2024-04-12

Product Details

Product Name: Osimertinib mesylate CAS No.: 1421373-66-1
EC-No.: 200-064-1 Min. Order: 1kg
Purity: 99% Supply Ability: 2000ton
Release date: 2024/04/12
Appearance: Light yellow crystalline powder

Osimertinib mesylate (AZD9291), the mesylate form of osimertinib, is an oral third-generation epidermal growth factor receptor (EGFR) tyrosine kinase (TKI) inhibitor.


AZD9291(mesylate), or oxitinib mesylate, is indicated for disease progression during or after previous treatment with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI). Treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) confirmed by testing with EGFRT790M mutation positive. AZD9291(mesylate) is highly selective, with an IC50 of 11.4nM and 12.9nM for T790M/L858R mutation and exon 19 deletion EGFR, respectively, and an inhibitor activity (IC50) of 494nM for wild-type EGFR. Ositinib is an irreversible inhibitor of EGFR and can form covalent bonds with molecular targets, so in theory the response lasts longer and the chance of resistance is correspondingly reduced.

Storage Condition

Keep in a cool and dry place

Transportation

By Sea or by Air(DHL/UPS/TNT/FEDEX/EMS)

Delivery Time

7-28 days

Payment

T/T, Western Union or Bitcoin

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Company Profile Introduction

Xi'an Haibo Biotechnology Co.,Ltd. is specialized in the study, production and sale of natural plant extract products,which are used in pharmaceuticaldietary supplement, food and cosmetic industries. Our company is located in Xian National High-tech Industrial Development Zone. Xian Haibo Biotech Co.,Ltd. has a number of departments including R&D, production, quality inspection, and market. The company's R&D center has a technical team specializing in research and developmentas well as advanced detection systems such as high-performance liquid chromatography, gas chromatography,and magnetic drive autoclave, experimental, pilot plant,and a number of scientific research institutions have established a good technical support relationship,with strong technical force. The company's production workshop has several plant extraction production lines, as well as advanced production equipment such as dynamic countercurrent extraction,column separatio

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