Osimertinib mesylate NEW
Price | Get Latest Price |
Package | 25kg |
Min. Order: | 1kg |
Supply Ability: | 2000ton |
Update Time: | 2024-04-12 |
Product Details
Product Name: Osimertinib mesylate | CAS No.: 1421373-66-1 |
EC-No.: 200-064-1 | Min. Order: 1kg |
Purity: 99% | Supply Ability: 2000ton |
Release date: 2024/04/12 | |
Appearance: Light yellow crystalline powder |
Osimertinib mesylate (AZD9291), the mesylate form of osimertinib, is an oral third-generation epidermal growth factor receptor (EGFR) tyrosine kinase (TKI) inhibitor.
AZD9291(mesylate), or oxitinib mesylate, is indicated for disease progression during or after previous treatment with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI). Treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) confirmed by testing with EGFRT790M mutation positive. AZD9291(mesylate) is highly selective, with an IC50 of 11.4nM and 12.9nM for T790M/L858R mutation and exon 19 deletion EGFR, respectively, and an inhibitor activity (IC50) of 494nM for wild-type EGFR. Ositinib is an irreversible inhibitor of EGFR and can form covalent bonds with molecular targets, so in theory the response lasts longer and the chance of resistance is correspondingly reduced.
Storage Condition | Keep in a cool and dry place |
Transportation | By Sea or by Air(DHL/UPS/TNT/FEDEX/EMS) |
Delivery Time | 7-28 days |
Payment | T/T, Western Union or Bitcoin |
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- Since: 2020-08-05
- Address: 804, Unit 2, Building 4, i City, No. 11, South Tangyan Road, High-tech Zone, Xi 'an, Shaanxi