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Postion:Product Catalog >Biochemical Engineering>Polypeptide>Octreotide acetate
Octreotide acetate
  • Octreotide acetate

Octreotide acetate

Price $1
Package 1piece
Min. Order: 1piece
Supply Ability: 1000
Update Time: 2025-04-29

Product Details

Product Name: Octreotide acetate CAS No.: 83150-76-9
Min. Order: 1piece Purity: 99%
Supply Ability: 1000 Release date: 2025/04/29

Article illustration

Chemical Name:Octreotide acetate

CAS:83150-76-9

Molecular Formula:C<sub>49</sub>H<sub>66</sub>N<sub>10</sub>O<sub>10</sub>S<sub>2</sub>·C<sub>2</sub>H<sub>4</sub>O<sub>2</sub>

Molecular Weight:1019.24 g/mol (free base: 931.61 g/mol)

Appearance:White or almost white powder

Solubility:Freely soluble in water; slightly soluble in ethanol

Stability:Stable at 2–8°C; protect from light and moisture

Mode of Action:Synthetic somatostatin analog; binds to somatostatin receptors (SSTR2/SSTR5) to inhibit growth hormone, glucagon, and insulin secretion.

Pharmacological Use:Treatment of acromegaly, neuroendocrine tumors (e.g., carcinoid syndrome), and esophageal varices bleeding.

Half-life:1.5–2 hours (subcutaneous); prolonged-release formulations available

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Octreotide acetate is a synthetic analog of somatostatin with prolonged activity and selective binding to SSTR2/SSTR5 receptors. Its clinical applications include:


Acromegaly: Suppresses growth hormone secretion.


Neuroendocrine Tumors: Controls symptoms (e.g., flushing/diarrhea in carcinoid syndrome).


GI Bleeding: Reduces portal hypertension in esophageal varices.


Advantages over Somatostatin:


Longer half-life (allows 2–3 daily SC injections or monthly depot formulations).


Higher specificity for target receptors.

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Test ParameterSpecificationTest MethodReference Standard
AppearanceWhite to off-white lyophilized powderVisual inspectionEP/USP
IdentificationComplies (HPLC retention time + MS)HPLC-PDA/MSEP/USP
Assay (HPLC)95.0%~105.0% (anhydrous basis)RP-HPLC (C18, 220nm)EP/USP
Related SubstancesTotal impurities ≤ 3.0%
Any single ≤ 1.5%
Gradient HPLCICH Q3A/B
Acetate Content5.0%~12.0%Ion chromatographyEP
Water Content≤ 8.0%Karl FischerEP/USP <921>
pH (1% solution)3.5~5.5PotentiometryEP/USP <791>
Heavy Metals≤ 20 ppmICP-MSUSP <232>/EP 2.4.8
Residual SolventsMeets ICH Q3C Class 2/3 limitsGC-FIDICH Q3C
Microbial LimitsTAMC ≤ 100 CFU/g
TYMC ≤ 50 CFU/g
Membrane filtrationEP/USP <61>
Endotoxin< 50 IU/mgLAL test (gel clot)EP/USP <85>
Specific Rotation-30° to -45° (c=1 in water)PolarimetryEP/USP <781>
Peptide Content≥ 90.0%Amino acid analysisEP
Biological Potency90%~115% of label claimCell-based bioassay (SSTR2/SSTR5)EP/In-house validated

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Company Profile Introduction

Wuhan Hao Rong Biotechnology Co., Ltd., located in East Lake high tech Development Zone, Wuhan, is a company specializing in the production and operation of chemical raw materials, flavors and fragrances, food additives, agrochemicals and other products. The company has first-class production equipment, advanced production technology, scientific management system, perfect detection means, and an excellent R & D team. The R & D center of the company has a technical team specialized in research and development, as well as a number of advanced detection, experiment and pilot equipment, and has established a good technical support relationship with a number of scientific research institutions, with strong technical force. The company has a wide range of products, in line with the quality of survival, service and development, customer-centric, integrity management philosophy, do our best to provide customers with quality and cheap raw materials. In addition, haorong also helps customers develop and implement customized system solutions. In these core areas of the chemical industry, haorong's core expertise covers chemicals and application technology, flexible asset management and customized services.

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  • Since: 2019-11-21
  • Address: Room E020, 4th Floor (1-3), Building 5, International Enterprise Center, No.1 Guanshan Second Road,
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