Nizatidine NEW
| Price | $29 |
| Package | 1mL |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Nizatidine | CAS No.: 76963-41-2 |
| Purity: 99.87% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Nizatidine |
| Description | Nizatidine (Acinon) is a competitive and reversible histamine H2-receptor antagonist with antacid activity. |
| In vitro | In rats, Nizatidine exhibits its maximum inhibitory effect on gastric acid secretion one hour after administration, with an EC50 value of 1.383 μMol/kg. Intravenous administration of Nizatidine (0.3-3 mg/kg) not only enhances gastrointestinal motility but also suppresses gastric acid secretion, achieving 50% of the maximal effect at a dose of 2.94 mg/kg and 90% at 19.6 mg/kg for rats. |
| In vivo | Nizatidine is a reversible, non-competitive inhibitor of acetylcholinesterase (IC50=6.7 μM, Ki=7.4 μM) and a selective antagonist of the histamine H2 receptor, effectively inhibiting gastric acid secretion (IC50=0.9 nM). |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 60 mg/mL (181.02 mM) H2O : 26 mg/mL (78.4 mM) Ethanol : 15 mg/mL (45.3 mM) |
| Keywords | cancer | gastroesophageal reflux disease | inhibit | intestines ulcers | hcc | Nizatidine | stomach | Inhibitor | erosive esophagitis | acid | Histamine Receptor | GERD |
| Inhibitors Related | Meclizine dihydrochloride | Lidocaine | 4-Methylbenzylidene camphor | Famotidine | Diethyltoluamide | Alginic acid | Methyl tridecanoate | Trimethylammonium chloride | Trazodone hydrochloride | Mianserin hydrochloride |
| Related Compound Libraries | Pain-Related Compound Library | Anti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | FDA-Approved Drug Library | GPCR Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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