NFAT Transcription Factor Regulator-1 NEW
Price | $39 | $85 | $145 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: NFAT Transcription Factor Regulator-1 | CAS No.: 245747-71-1 |
Purity: 99.11% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | NFAT Transcription Factor Regulator-1 |
Description | NFAT Transcription Factor Regulator-1 is a synthesis inhibitor of IL-2 with an IC50 of 182 nM. |
In vitro | NFAT Transcription Factor Regulator-1 inhibits IL-2 synthesis(IC50 of 182 nM).?NFAT Transcription Factor Regulator-1 inhibits human and rat PBMC proliferation with IC50s of 82 and 146 nM, respectively.?NFAT Transcription Factor Regulator-1 is able to inhibit IL-4 and IL-5 production in human T-cell lines with similar potency to its effects on IL-2 release. |
In vivo | NFAT Transcription Factor Regulator-1 demonstrates an inhibitory potency on T-cell IL-2 production that is approximately 10 times greater than cyclosporine, requiring doses of 3.0 mg/kg and 30 mg/kg, respectively, for comparable effects. In vivo studies in monkeys further reveal the potential of NFAT Transcription Factor Regulator-1 to block T-cell cytokine production effectively, suggesting its viability as a transplantation aid comparable to cyclosporine[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 50 mg/mL (120.11 mM), Sonication is recommended. |
Keywords | NFAT Transcription Factor Regulator-1 | NFAT Transcription Factor Regulator 1 | NFAT Transcription Factor Regulator1 |
Inhibitors Related | Inosine pranobex | Apilimod mesylate | Amlexanox | Dexamethasone acetate | L-Arginine | Bergenin | α-Terpineol | Diallyl disulfide | Linalool | Apilimod |
Related Compound Libraries | Bioactive Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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