Product Name:    Neomycin sulfate

Synonyms:    NEOMYCIN SULPHATE pure;mycigient;neobiotic;neofracin;neo-mantlecreme;neomix;neomycinesulfate;newfrancef

CAS:    1405-10-3

MF:    C23H48N6O17S

MW:    712.72

EINECS:    215-773-1

Product Categories:    13C & 2H Sugars;Aminoglycosides (Antibiotics for Research and Experimental Use);Antibiotics for Research and Experimental Use;Biochemistry;Antibiotic Explorer;Carbohydrates & Derivatives;AminoglycosidesAlphabetic;Antibiotics;Chemical Structure;N;NA - NI;AminoglycosidesAntibiotics;Antibacterial;Peptide Synthesis/Antibiotics;Antibiotics A to;Antibiotics by Application;Antibiotics N-SAntibiotics;Antineoplastic and Immunosuppressive AntibioticsAntibiotics;Chemical Structure Class;Genetic Marker SelectionAntibiotics;Interferes with Protein SynthesisSpectrum of Activity;L - ZMore...Close...;Mechanism of Action;API's;MYCIFRADIN;antibiotic;Antimicrobial;API;1405-10-3

Neomycin sulfate is an aminoglycoside antibiotic and calcium channel protein inhibitor. Neomycin sulfate also binds to prokaryotic ribosomes inhibiting translation and is effective against gram-positive and gram-negative bacteria. Neomycin sulfate inhibits PLC (Phospholipase C) via binding to inositol phospholipids. It also inhibits phosphatidylcholine-PLD activity and induces Ca2+ mobilization and PLA2 activation in human platelets. Neomycin sulfate inhibits DNase I induced DNA degradation. It is used to prevent or treat skin infections caused by bacteria. It is not effective against fungal or viral infections.