Neomycin sulfate is an aminoglycoside antibiotic. The product has a good antibacterial effect on enterobacteriaceae bacteria such as Staphylococcus (methicillin-sensitive strains), Corynebacterium, Escherichia coli, Klebsiella, Proteus, etc. Chemicalbook has poor activity on streptococcus, Streptococcus pneumoniae and Enterococcus in each group. Pseudomonas aeruginosa, anaerobic bacteria and other drug resistant to this product. The bacteria had partial or complete cross-resistance to streptomycin, neomycin, kanamycin and gentamicin.