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Postion:Product Catalog >NCGC00378430
NCGC00378430
  • NCGC00378430

NCGC00378430 NEW

Price $68 $163 $245
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-18

Product Details

Product Name: NCGC00378430 CAS No.: 920650-00-6
Purity: 99.74% Supply Ability: 10g
Release date: 2024/11/18

Product Introduction

Bioactivity

名稱NCGC00378430
描述NCGC00378430 is a potent SIX1/EYA2 interaction inhibitor that disrupts the [SIX1/EYA2] complex, EMT, and metastasis.
體外活性NCGC00378430 reduces the SIX1/EYA2 interaction.?8430 partially reversed transcriptional and metabolic profiles mediated by SIX1 overexpression and reversed SIX1-induced TGFβ signaling and EMT.
體內(nèi)活性NCGC00378430?was well tolerated when delivered to mice and significantly suppressed breast cancer associated metastasis in vivo without significantly altering primary tumor growth.
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 90 mg/mL (203.85 mM), Sonication is recommended.
關(guān)鍵字Inhibitor | T47D | E-CAD | MCF7 | Phosphatase | TGF-β | NCGC00378430 | inhibit | SIX1 | p-Smad3 | breast | EMT | cancer | FN1 | transcriptional | NCGC 00378430 | NCGC-00378430 | EYA2
相關(guān)產(chǎn)品PTP1B-IN-22 | Disodium monofluorophosphate | β-Glycerophosphate disodium salt pentahydrate | MLS000544460 | Tartaric acid disodium dihydrate | Cyclosporine | Stearic acid | Cis-5-Norbornene-exo-2,3-dicarboxylic Anhydride | L-Ascorbic acid 2-phosphate magnesium | Cyclosporin A | Trimyristin | β-Glycerophosphate disodium salt hydrate
相關(guān)庫糖代謝化合物庫 | 經(jīng)典已知活性庫 | 抗乳腺癌化合物庫 | 抑制劑庫 | 代謝化合物庫 | 已知活性化合物庫 | 抗癌化合物庫 | 磷酸酶抑制劑化合物庫 | 抗癌活性化合物庫 | TGF-β/Smad靶點化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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