Manufacturer Provide API Anti-Inflammatory Naproxen Sodium Powder Material CAS26159-34-2 Naproxen Sodium

Introduction

1.Product Name:  Naproxen Sodium

2.Other Name:6-methoxy-alpha-methyl-,sodiumsalt,(s)-2-naphthaleneaceticaci;6-methoxy-alpha-methyl-,sodiumsalt,l-(-)-2-naphthaleneaceticaci;

3..CAS NO:26159-34-2

4.Purity: 99%min
5.Appearance:White Powder

6.Molecular formula: C14H13O3.Na

7.Molecular weight:252.24

8.Melting Point :250-251°C

9.Storage:Keep in dark place,Inert atmosphere,Room temperature

Naproxen sodium is a kind of non-steroidal anti-inflammatory analgesic that is easier to be tolerated by humans. It belongs to the phenylpropionic acid compound and exerts anti-inflammatory and analgesic effects by inhibiting the synthesis of prostaglandins.
It is clinically suitable for alleviating various mild to moderate pains, such as pain after tooth extraction and other operations, primary dysmenorrhea and headaches. It is also suitable for rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, juvenile arthritis (Juvenilearthritis), tendinitis, bursitis and acute gouty arthritis. Limits have the effect of relieving symptoms. Psoriatic arthritis and Reiter's syndrome can also be treated with this product. Compared with ibuprofen, fenoprofen, aspirin, sulindac and indomethacin, the effect of symptom relief is similar.
Efficacy and effect
Naproxen sodium has strong anti-inflammatory and analgesic effects, and its main biological effects are:
(1) Inhibit the activity of prostaglandin synthase, thereby reducing capillary permeability;
(2) Reduce the production of superoxide by macrophages to play an anti-inflammatory effect;
(3) Stimulate T inhibitory cell activity;
(4) Reduce pain sensitivity. Compared with ibuprofen, fenoprofen, aspirin, sulindac and indomethacin, the symptom relief effect is similar, but the incidence and severity of adverse reactions in the gastrointestinal tract and nervous system are lower.