N-Boc-4-hydroxy-L-proline methyl ester NEW
| Price | Get Latest Price | |
| Package | 5mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: N-Boc-4-hydroxy-L-proline methyl ester | CAS No.: 102195-79-9 |
| Purity: ≥98% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | N-Boc-4-hydroxy-L-proline methyl ester |
| Description | N-Boc-cis-4-hydroxy-L-proline methyl ester serves as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and functions as an alkyl chain-based PROTAC linker for PROTAC construction [2]. |
| In vitro | ADCs consist of an antibody linked to a cytotoxin via an ADC linker, enabling them to deliver cytotoxic agents to specific cells [1]. PROTACs are bifunctional molecules with two ligands connected by a linker: one binds to an E3 ubiquitin ligase and the other to the target protein, leveraging the cell's ubiquitin-proteasome system for the selective degradation of target proteins [2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Keywords | N-Boc-4-hydroxy-L-proline methyl ester | Compound FL0195 |
| Inhibitors Related | N-Boc-PEG5-bromide | Succinic anhydride | DSS Crosslinker | Val-cit-PAB-OH | Fmoc-8-amino-3,6-dioxaoctanoic acid | Fmoc-Gly-Gly-OH | Boc-NH-PEG4-CH2COOH | EMCS | DSG Crosslinker | FMoc-Val-Cit-PAB-PNP |
| Related Compound Libraries | Featured Fragment Library | High Solubility Fragment Library | High Solubility 3D Diversity Fragment Library | High Solubility Micro Fragment Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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