N-Arachidonyl Maleimide NEW
Price | $53 | $108 |
Package | 2mg | 5mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: N-Arachidonyl Maleimide | CAS No.: 876305-42-9 |
Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | N-Arachidonyl Maleimide |
Description | N-Arachidonyl maleimide, a potent and irreversible monoacylglycerol lipase (MAGL) inhibitor, has an IC50 value of 140 nM [1]. |
In vitro | N-Arachidonyl maleimide, a presumed MAGL inhibitor, is utilized for adjusting the impact of 2-arachidonyl glycerol (2-AG). It elevates endogenous 2-AG levels in the brain and inhibits cerebellar membrane-mediated 2-AG degradation effectively at a low concentration (IC 50, 140 nM) [1]. |
In vivo | 2-AG (1, 3, and 10 mg/kg) produces significant and dose-dependent hypothermia, inhibition of locomotor activity, antinociception, and catalepsy when combined with a 1 mg/kg dose of N-Arachidonyl maleimide [1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Keywords | N-Arachidonyl Maleimide | NArachidonyl Maleimide | N Arachidonyl Maleimide |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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