N-Acetyl-L-cysteine ethyl ester CAS:59587-09-6 N-Acetylcysteine ethylester

Product Name:N-Acetyl-L-cysteine ethyl ester

Synonyms:ethyl (2R)-2-acetamido-3-sulfanylpropanoate;Acetylcysteine Impurity H;101242;2-acetamido-3-mercaptopropanoic acid ethyl ester;Ethyl N-acetyl-L-cysteinate;N-Acetyl-L-cysteine ethyl ester;L-Cysteine, N-acetyl-, ethyl ester;N-Acetylcysteine ethylester

CAS:59587-09-6

MF:C7H13NO3S

MW:191.25

Melting point:44.1-44.5 °C

Boiling point:337.6±32.0 °C(Predicted)

density:1.138±0.06 g/cm3(Predicted)

storage temp.:2-8°C

solubility:DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 10 mg/ml

Description   

N-acetyl-L-Cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC; ). It has enhanced cell permeability in isolated perfused rat liver compared to NAC. N-acetyl-L-Cysteine ethyl ester (1 mM) prevents tert-butyl hydroperoxide-induced formation of methemoglobin in isolated human red blood cells. It increases glutathione levels in rat liver, kidney, heart, testis, and brain when administered at a dose of 50 mg/kg twice per day for two weeks. N-acetyl-L-Cysteine ethyl ester reduces increases in plasma aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels induced by paracetamol (acetaminophen; ) in rats.